β-Nicotinamide mononucleotide

Research use only not for human use.

Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway.

Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid nicotinamide is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT EC 2.7.7.1) which is a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily catalyzes the reaction NMN + ATP <=> Nicotinamide adenine dinucleotide (NAD) + PPi representing the final step in the biosynthesis of NAD. NAD is a molecule that plays a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis. Circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions.

β-NM

Others

Other Targets

Others

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1094-61-7

334.22

C11H15N2O8P

>98% (HPLC)

H2O:83.33 mg/mL (249.33 mM; Need ultrasonic)

NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O

((2R3S4R5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate

(-20℃)

With Ice Pack

≥ 2 years