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β-Nicotinamide mononucleotide

CAS No. 1094-61-7

β-Nicotinamide mononucleotide ( β-NM )

Catalog No. M19547 CAS No. 1094-61-7

Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 138 In Stock
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Biological Information

  • Product Name
    β-Nicotinamide mononucleotide
  • Note
    Research use only not for human use.
  • Brief Description
    Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway.
  • Description
    Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid nicotinamide is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT EC 2.7.7.1) which is a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily catalyzes the reaction NMN + ATP <=> Nicotinamide adenine dinucleotide (NAD) + PPi representing the final step in the biosynthesis of NAD. NAD is a molecule that plays a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis. Circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions.
  • Synonyms
    β-NM
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1094-61-7
  • Formula Weight
    334.22
  • Molecular Formula
    C11H15N2O8P
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:83.33 mg/mL (249.33 mM; Need ultrasonic)
  • SMILES
    NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O
  • Chemical Name
    ((2R3S4R5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ohdoi C et al. Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 15;792(1):123-30.
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